Instead of only one specific link, they found many. The first confirmed the earlier observations of a change in the microbiome. As alcoholism progressed, the gut underwent a form of dysbiosis. The levels of good bacteria, such as the probiotic Lactobacillus, dropped while those of potential pathogens rose. They also highlighted an overgrowth of these bad bacteria leading to an increase in toxins and other liver-damaging chemicals. Inflammation would subsequently occur, leading to increased permeability of the gut. At this point, those damaging byproducts would be easily translocated to the blood serum and the liver. Over time, the damage would become unstoppable and eventually, disease would occur.