It was one such push that led to his biggest innovation in molecular visualization. Using a computer algorithm he developed and nuclear magnetic resonance imaging, Al-Hashimi recorded the atomic-scale contortions of RNA and DNA, long thought of in biology as relatively inflexible structures. Instead of holding one predominant form, Al-Hashimi found, RNA bends and wiggles into a predictable series of shapes as its atoms rotate around their bonds. Each shape is a potential target for RNA-attacking drugs. Using this new method, Al-Hashimi has already identified one molecule, called netilmicin, that can stop HIV replication by latching onto RNA where one of the virus's essential proteins otherwise would.