Jay Fishman, director of transplant infectious diseases at Massachusetts General Hospital in Boston, proposes using a virus that causes encephalitis, an inflammation of the brain's casing. Herpes would work, and so would West Nile, but attaching a prion to a virus is, Fishman adds, "a fairly unlikely" scenario. And then, after infection, we need to stop the prion takeover so that our zombies don't go completely comatose, their minds rendered entirely useless. Schlozman suggests adding sodium bicarbonate to induce metabolic alkalosis, which raises the body's pH and makes it difficult for proteins like prions to proliferate. With alkalosis, he says, "you'd have seizures, twitching, and just look awful like a zombie."