We know how it works in low doses, and it’s not a complete anesthetic. It’s not guaranteed that everyone will go to sleep with the drug, because people have paradoxical reactions to it. We [doctors] have also never administered these doses to humans before and we have no idea of impact. We know that states’ presupposition is if you administer 10 times the drug’s dosage, it’s 10 times as effective. But that’s a factual error—the ceiling effect, which is well described in literature, says that if you give more of a drug, it doesn’t do anything. It’s like when you put too much sugar in your iced tea, at a certain point you just can’t dissolve any more—you get to a saturation point. That’s exactly what happens here—you get to a saturation point for the available receptors for drug, and adding more doesn’t increase the effect.