Plus, in the past 50 or so years, we've gotten a lot better at creating medications that reduce things like high blood pressure, cholesterol, and triglycerides. These drug discoveries were in huge part thanks to families that had these unfortunate variants. For example, researchers studying familial hypercholesterolemia were able to understand how those mutations work and create drugs to fix the problem, effectively and significantly lowering cholesterol levels not just for people with those rare genes, but for everyone. And there's a lot we are still figuring out. Recent research on the microbiome (the bacteria that live on and in your gut, that are, in fact, also influenced by a diet, gene, and lifestyle combo) found that certain bacteria, when simply sprayed on the skin to treat acne, may also lower blood pressure.