If you eat 10 McRib sandwiches, the first thing that will probably happen is that you will feel ill, says Leslie Bonci, a registered dietician based in Pittsburgh. The levels of triglycerides, or fat in your blood, will spike—elevated triglycerides are a secondary risk factor for heart disease, "no matter if you're 82 or 22," Bonci says. So much food at once will also raise your blood pressure. "When you consume all that at once, it puts the body in a state of stress," Bonci says. The sodium will make you thirsty but prevent your gut from absorbing the water, making you bloated and puffy. If you have a history of acid reflux, you're going to be pounding the antacids for a few hours at least, Bonci says, because of all the fat you're consuming. And if you have pancreatitis, the last thing you'd want to do is overload your system with that much fat and sodium.