But you can have too much of a good thing. The harder you work your muscles, the more those fibers will break down. During that process, a protein called myoglobin, as well as various electrolytes and enzymes (particularly creatine kinase), are released into the bloodstream and filtered through the liver and kidneys. In extremely high amounts, they can be too much for those filtering and processing organs to handle, and they start to build up. Without treatment, this all eventually results in kidney damage, which, when prolonged, is a life-threatening condition. But once identified, doctors can treat rhabdo with intravenous fluids as well as other medications to help flush the toxins out.