The concept of a relationship with germs may seem perplexing at first. After all, how could we, as sentient beings capable of thought and action have anything to do with the most basic life forms on the planet? Yet every moment is shared with germs and our contentment is dependent on how we co-exist with them. If we keep our bodies full of good bacteria, we’re happy; if we allow unhealthy ones to enter, either through infection or dysbiosis, we end up miserable. Taking this one step further, thanks to the work of the Human Microbiome Project and other researchers and organizations, we are learning that we may be able to prevent and in some cases reverse chronic health conditions by simply improving our connection with our microbial residents.