Holt, 59, says the U.S. is at a critical juncture in its support of science and engineering. A new president, for example, could end the recent politicization of science. But he feels we also need to make a fiscal commitment. Our economy is fueled by innovation, yet, Holt contends, we're not laying the groundwork for future breakthroughs. At press time, he was fighting for $500 million in emergency funding to revitalize programs at the Department of Energy's Office of Science, the National Science Foundation, and the National Institute of Standards and Technology.