A team at the University of Texas has created a fat-burning drug that doesn't so much burn fat as it seeks and destroys it. Instead of suppressing appetite or increasing metabolism, this drug systematically destroys the blood supply to fat tissue--and in a recent study, obese rhesus monkeys lost 11 percent of their body weight when treated with the drug.
The drug works in a totally different way than other drugs, which seek to replace or supplant the ways humans eat and behave by altering appetite or energy level. This one works on the inside, and it's actually kind of terrifying in detail. It has a homing agent that seeks blood supply to fatty tissue, zooms right over to it and attaches itself. Then it delivers a peptide which kills the blood cells, at which point the fat cells are simply absorbed.
The team tested the drug first on mice, and now on "spontaneously obese" rhesus monkeys. "Spontaneously obese" in this case means the monkeys in question became obese in the old-fashioned way: binge-eating and a lack of exercise. It's a naturally occurring behavior in this species, and it's convenient for testing. Compared with the control group, which saw no change, the rhesus monkeys treated with the drug saw reductions in body weight, body mass index, and even waistline measurements (scientific term: abdominal circumference). It's a big deal that the drug worked on primates as well--many weight-loss drugs fail in the move from rodent testing to primate testing.
The drug, luckily, did not seem to adversely affect lean monkeys, nor did it have any perceptible change on mood in the treated obese monkeys. Obese monkeys: yet another valuable tool.
Sign me up to be a tester. Maybe I can finally lose this frackin weight!
So it's not just humans that seem to be naturally inclined to sedentary lifestyles when life provides all needs in great abundance, but animals too. Means obesity is less of a sentient thing and more of a luxury thing.
While I'm not opposed to appetite suppressors and metabolic and energy rate enhancers, a dietary narcotic that directly dissolves fat would be the best thing for loosing weight for people with low metabolic rates. For these individuals weight loss is hard because of the body's inability to quickly and effectively process food and excrete waist (hence the appetite suppressants, and metabolic rate enhancers).
This drug could be a cure for obesity. Of course, the goal would be to get people to live better so that obesity does not creep up on them again. Certain drugs can not be used as a scapegoat for avoiding the ill effects of a sedentary lifestyle.
Finally I can have the sleek sexy monkeys I have always dreamed of.
And if you are fat all over, 300lb ... will this kill you since it destroys blood supply to all over the body?! :O
Blood supply to fat cells. That's pretty specific. Doesn't kill blood supply to the rest of the body like muscles, and the brain. Gotta wonder though, if nano-technology is at play here. hmmmm...
Does this have anything to do with the type of research of the modified mice in the previous post?? I really wish we could find out more on the stuff that is posted, like the negatives. Are there any negatives to this product at all?
What could possibly be negative about consuming drugs built to destroy blood cells?
Seems like a good idea, but considering the apparent nature of this "drug" it should require extensive testing before being made available at your local Pharmacist... and a waver.
This may not be as good of a cure, even if it is very effective without many adverse side-effects. This kills Fat cells after they've been formed. Its essentially the same thing as lipo-suction, in that you just remove the fat after the fact.
While this drug would be better than lipo-suction, the issue is that most of the negative health effects come from the dietary conditions associated with obesity, as oppose to the actual existance of the fat cells. The strain on the body, the aesthetics, and other things that stem from a high body fat percentage will be fixed; high blood pressure, artherosclerosis, pancreatic clogging (diabetes) and other physiological issues that stem from poor diet will not be affected.
As phoenix 1012 said, the goal is to make people live healthier lives. If you can give them back a pleasing body, especially in such a rapid manner, they may perish the thought of ever letting themselves become that large again, and hopfully take better care of themselves the second time around. However, this drug won't serve as an easy-way-out to better health.
...or all the fat people will buy these drugs and eat more than ever. We live in a society where we don't want to be responsible for our actions. People want to live sluggish, sloth filled lives and still look like an athlete that works out 4hrs a day. It's a fantasy and a dream.
Work with what you were born with.
If you are overweight, it's quite easy to lose all the weight, it's called will power, diet and exercise. That will make you feel a million times better than popping pills.
aldrons last hope i agree with you for once.
@Aldrons Last Hope
+1 this is majorly true but like brain said there are some people that just want to lose it fast if they can keep the mindset of live healthy even with this alternative i see this as a good idea. however if they keep the same mindset of pigging out then this will become the newest legal drug and most likely will be bought over and over.I don't know how but i think repeated doses would eventually cause some unwanted mutation in the way the drug works.
I hope it work but I see the law of unintended consecrated kicking in somewhere down the road
So fat people are really just large fat monkeys?
What a waste of time and money. Exercise and healthy diet will slim a person down. Can't their efforts be better used? Cancer or Alzheimer's or Crohn. Anything other than some result of laying around and eating BBQ and fried foods would have been better use of their time.
Sign me up. Being 40 and in good shape, I'm tired of working out and not having the six pack no matter what I do.
i eat salad often, a very healthy diet over all. i walk alot, up to 10 miles a day. knee injuries prevent a run or a jog. up to 300 crunches a day. im a solid 230 for the past 10 years. this could help me drop the rest of the weight. id like to be back at 200 atleast
Hopefully this drug dont dissolve too much fat, as we still need fat for reserve energy. Also what about the opposite? What if anerexic people or models take this to get thinner? Wont that be dangerous? And sorry for any grammar or spelling mistakes, my phone dont have spell check.
We humans are naturally addicted to food. Eating just feels great. Combine that with this drug to lose weight and we can be addicted to both food and the drug, never really facing the original problem.
But still, I hope it does help the sick. Once a person becomes excessively fat (however they got there in the first place), fat does produce on its own estrogen which inspires and encourages more fat cells. The cycle then is terrible.
You know, I'm digging this... Once your fat cells expand to their max size they divide to create more capacity via more fat cells. You can reduce your body fat by shrinking your fat cells, but you can NEVER reduce your fat cell count, at least not naturally. (look it up if you don't believe me)
I work out 5-6 times per week, weight training and cardio. I ran in a few marathons and half marathons. I eat salad twice a day and 5-6 meals per day. Nevertheless it seems I still can't get down to single digit body fat. At 23 I was averaging 5% body fat and now at 36 I can't get below 11% - I've been trying for 3 years. I did have a few "fat years" after college and I wonder if the addition of those new fat cells are keeping me where I'm at. If these pills really do "remove" fat cells, then a person like me could revert back to an original number of fat cells and hopefully get the results they are working hard to achieve.
Side effects may include:
Heart reversal, navel discharge, skin faliure, full body shrinkage, reincarnation, spontaneous combustion, planned combustion, male pregnancy, post-modern apathy, black plague, deja vu, alien abduction, prenatal baldness, homocidal manial, dry mouth, dry blood, sissyness, loss of all emotion and assimilation into the hive mind, addiction, bad hair days, severe addiction, deja vu, lumbago, Saint Vitus dance, "permaant winky retreat", oily discharge, fecal complexion, fear of clowns, molting or shedding of exoskeleton, inbreeding, presbetryianisim, inability to use spoons, mystic enlightenment, funk, devil's haircut, stinkfist, electric head, x-ray vision and super strength, demagoguery, piano legs, change in complexion, change in ethnicity, Russian accent, entropy, tin ear, comical Jesse Helms like jowels, siamese twin, Veitnam War flashbacks, loss of balance, the munchies, crab lice, explosive diarhea, evil eye and tendency to become farklempt.
@niceslamander don’t hold it against yourself, it happens from tie to time :D
@Brian, try creatine & 100% whey protein and cardio for 40 mins a day and crunches.
The drug reduces fat, it doesn’t create muscle. A six-pack is muscle.
@Heavy Hand no matter the side effects, people will still take it.
The only thing that I see as a threat here, is humans abusing this fat burning drug. If so many humans could lose so many fat (Preferably ones that are fat or obese) then they might eat more then usual, and so, a greater depletion in livestock, grains, etc.
Hope no one takes my word fat or obese the negative way, it's just thought.