In a major step toward understanding cancer, one of the biggest problems bedeviling modern medicine, scientists have now cracked the genetic code for two of the most common cancers. This marks just the beginning of an international effort to catalog all the genes that go wrong among the many types of human cancer, the BBC reports.
Too much time spent under the sun apparently leads to most of the 30,000 mutations contained within the DNA code for melanoma, or skin cancer. Outside experts told the BBC that no previous study has managed to link specific mutations to their causes.
Wellcome Trust scientists also found more than 23,000 errors in the lung cancer DNA code, with most caused by cigarette smoke exposure. A typical smoker might get one new mutation, possibly harmless but also possibly a cancer trigger, for every 15 cigarettes that they smoke.
The new cancer maps could lead to better blood tests for diagnosing the respective cancers, as well as better targeted drugs. Blood tests might even reveal the DNA patterns that suggest cancer lies on the horizon.
The International Cancer Genome Consortium still expects to spend hundreds of thousands of dollars in cracking the code of the many human cancers. The U.S. has the job of studying cancers of the brain, ovary and pancreas, while the UK examines breast cancer. China is tasked with decoding stomach cancer, Japan is focused on liver cancer, and India has taken a crack at mouth cancer.This painstaking research can only help futuristic treatment efforts, such as nanoparticle-targeted lasers and do-it-all nanoparticles that can track, tag and kill cancer cells. But those cancer-resistant mole rats should still count their lucky stars.
[via BBC]
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Hopefully innovations, discoveries and applications come quicker to eradicate diseases in people.
Honestly I hope that these innovations, discoveries and applications never come. I believe that if cancer is ever cured it would be the most significant medical breakthrough ever, but there need to be some sort of ''check'' on the population. We are over populated as is and are taxing the earth and its resources at an alarming rate. I'm sure that you would probably want to ask me how I would feel if I were diagnosed with cancer and I am sure that I would want there to be a cure, but as Woody Allen puts it "mankind faces a crossroads. One path leads to despair and utter hopelessness. The other, to total extinction. Let us pray we have the wisdom to choose correctly."
I believe that the real focus should be placed on neurodegenerative diseases that impact the quality of life without necessarily ending it. Parkinson's and other debilitating neural diseases* should take priority over 'terminal' illnesses. Think of it as triage, you would want to treat the patients with the most severe illnesses but are still likely to survive.
Seeing as whether you treat people with Parkinson's* or not they will still be alive, they should have the best chance for a cure.
This makes me want to study cancer in the UK
your an idiot sir. that is very cold. You would not be saying that if you had 2 months to live and couldnt breath well because you have lung cancer. Overpopulation is a problem, but the way to solve that is not to let diseases ravage families.
The more we can progress the faster we can fix problems. If we stay in the dark ages letting plagues solve our problems for us, we wont get anywhere.
i hope you get cancer for saying something so foolish. Population control is important, but that doesnt mean we need a way to cull the herd. Advance and invent.
I don't think you needed to react that way Thumper. You agree population control is important, yet offer no alternative to disease. People (myself included) find euthanasia immoral and birth caps sad, so why not let nature do it all for us? If we cure every disease out there, we will all die of starvation and over population. Doesn't mean I don't believe in medical innovation, this is just my response to your comment.
Interesting article about Cancer Research. Having International collaboration on research is excellent. I hope that each country's endeavors are in synced communication (to learn things from each other), if not I hope that small competitions are created (such as x-prize) to promote "outside the box" forward thinking and creativeness in Cancer DNA sequencing. I look forward to the day when Radiation treatment and Chemotherapy will be looked upon as barbaric and and primitive. Such as, long ago when brain surgery was once done with a chisel and a mallet. God, I wish that day would come. I hope and pray...
I'm curious if each country's research has any association with the majority of Cancer patients in each country? And if so, are there alternatives in which to warn the general public about health related problems (ie water, food, air, etc.)? Having been to each of the country's named I could make assumptions about each one, (my humble ramblings)...
China seeking stomach cancer research, over 90% of their water is incredibly polluted - unsafe to drink. But people do anyhow...
Japan seeking liver cancer research, I'd suggest maybe a majority of the populous has a drinking problem. Could it be that becoming an technological superpower has caused massive competition, high stress/high pressure life/work/family, etc.
India seeking mouth cancer research, maybe, just maybe because of the large amount of industrial smog, industrial sewage, general populace sewage, etc in the water supply and which is not taken care of properly.
UK, Not sure, old lead pipes, to much beer?? no idea???
USA, fast foods, synthetic foods, etc.
Thanks for hard work guys, keep it up!!! Please Destroy Cancer.
Fox
What about Mutations in relation to Marijauna
Curing all cancer would only increase the population by a small factor after the first decade or two.
Most cancer paitents are old, and so a cure for cancer will only extend life by a decade or so. Yes, that will lead to an increase in the number of people living on the planet, but will have no affect on the increase of further generations, making it a limiting factor as life exspectancy increases.
Now, for children with cancer, it will increase the number of viable adult breeders to include those who are healed. That, however, is a rather small portion of humanity, and likely nowhere near on par to things like digging wells in Africa or handing out mosquito nets to reduce malaria.
The real downside to curing cancer is that once you have a cure, people cease being cautious about the factors that cause a disease.
Hello Thumper,
Thank you for your well wishes. I just wanted to let you know that you clearly didn't read my whole post as I had preemptively answered your question. It is understandable why many would feel so passionately about finding a cure. I am just trying to yield a little insight on population control. It is a dirty job there is no dancing around the subject, you are either decreasing birthrates or increasing deathrates. I just hope that not everyone is so close minded that innovation and invention is the key, unless you believe we will soon be colonizing some other planet or moon in the near future.
We can't shrug off these important decisions and spout off about how down the road we will be more ready to handle it. That may be true but,it sounds an awful lot like procrastination to me. In order for innovation and invention to work in the future, there would have to be people innovating and inventing remedies for this solution now.
You say it yourself that population control is important. Is that all you have to say about it? Or is your solution simply to wish cancer upon me and everyone else overly concerned with population control while curing the others.
No political figure has addressed the issue (that I can recall), and I am sure that if one did they would not get elected or hold office very long. We have to get over the stigma that comes when talking about people dying because...well... they die...we die.
We need to stop pretending we are living in the perfect world and I sure hope that innovation and invention doesn't get us there. What would we be then? Our pains and losses are in integral part of our humanity and without them who knows what we would become.
Also, cancer is not going to bring about any cataclysmic events, we have lived with it up to this point and I say we have done pretty well. Overpopulation on the other hand can bring about many irreversible repercussions (unless innovation and invention can save us)*. For example the deforestation for food and housing will increa... blah... blah... blah; we have all heard it before, so why aren't we doing anything about it. If any of us 'privileged' people lived in an overpopulated area. Our focus would shift towards surviving today, never mind diseases I could get some time down the road, I have no food housing or job and neither do the thousands of people around me. Heck, with all of the disease and suffering these people are always around I am sure that some of them would choose to get cancer and be able to move away. These people see things far worse than cancer on a daily basis.
Anyway,I guess I can hope that you are forced to leave in some overpopulated inner city. Does that make us even thumper?
Also Thumper,
'The more we can progress the faster we can fix problems.' This is a mindset we cannot have. This is not some sort of race, we can't just go about and see a problem and fix it. We need to slow down and take into account what new problems will arise from the solution of this one. We need to decide which problems are worth living with.
keeping cancer around to help kill people and the rest of the issues is not a solution. its not even on topic stay on topic. this article is abotu finding a cure for cancer. raz you have no solution so stfu. but one thing i liek about life is that i bet you will get cancer. and then you will be a bitch and rant how you want a cure. and did you use a quote from woody allen? :p
Cancer needs to be cured its a horrible disease, we're still using slight variations on 50 year old medicines, based on platinum research of a century ago. The medicine is nearly as bad as the cancer.
This research is important to find not only primary genetic mutation that causes the initial cancer but secondary and tertiary mutations that are done in the cancer cells themselves to promote their survival, is an ancient retrovirus component that was incorporated a billion years ago reactivated?, why are the common mutations to evade immune system and mitochondrial preprogrammed death circumvented commonly in cancers, is it natural selection or a component holdover from single celled existance?
Theres a lot of questions, still too few answers. Hopefully research like this will change that.
I can't believe we're having a conversation about population control with cancer. How society has been degraded, you want population control, use a bullet in the head, it's faster and more humane. You want environmental resource control start with yourself.
I find it interesting so many "independently" come to the conclusion of population control recently. The developed nations aren't in particular jeopardy of starvation unless the bureaucrats get their way. So why? The US has a small population for the size, Canada an even more disproportionate amount of land and people. But the conversation is based in the western world, not in the countries that are desperate for population control. Population in the west has already leveled off, it happens that way naturally when times are easier, its a natural control that we do automatically. This conversation being had now is not a coincidence its part of a larger controlled idea of population control not just in numbers but in every aspect of peoples lives. Rationalizing evil is easy, people just tell themselves they are doing good, its for the environment, if we do nothing people will die, its better this way.
Yes i am mad, not just because I had someone die of cancer and someone here has the audacity to hope not to cure it, but the sickness that underlies that way of thinking has invaded this society so much like a cancer, a part of it that turns against it and attempts to destroy it. Progressivism is a cancer of the body politic. Both the disease that destroys it and the maggots that long to feed on the corpse.
- razgriz3 -
Overpopulation can be, and will be solved by the colonization of space. Colonizing other planets like Mars, the Moon, building space stations in orbit around the Earth, etc. Our resources problem can be solved by mining asteroids, and there's plenty in the asteroid belt between Mars and Jupiter. If you want people to stop having babies, tell the poverty stricken countries in Africa to stop having so many children, and tell countries like China to put harsher limits on having children, which they already have. Honestly, expanding into space will solve a lot of problems, of course it will create new problems, but life is never without problems.
25 years ago I proposed the Cell Death Signal Gene theory, and although I had support from a leading scientist at M.D.Anderson I was blacklisted by the U of Waterloo (RIM/the Blackberry) in order for them to commit federal fraud. A former US Surgeon has regretted my treatment , see www,.cancerfraudbadbiotech.com . What these researchers are missing is that the mutations are bypassing this controller which stops cancers from growing.Hopefully it won't take another 25 years for them to "discover " this.Ask yourselves how many people died in the last 25 years from cancer that didn't have to? Anyone you loved?
Thank you Mycellium. I'm in agreement that some people come around to their own conclusion that 'population control' is a viable solution... Again I am in agreement. It is not. Just in case others are wondering. I've been thinking how incredibly absurd the talk of population control has reached this far into this topic of discussion. I equate it in the same line of thinking as saying curse words or using cuss words - let me explain - the majority of individuals who curse/use cuss words - seem to me - are lacking any real helpful insight in conversations, lacking imagination, and have a deficiency of creativity and sometimes education,(granted, there are some incredible poets out there) I'd rather see individuals come up with their own thoughts and provoking idea's, inventions, and new conclusions, in which healthy use of their vocabulary is used in order to describe their thoughts, feels, expressions and ideas. People need to be careful because if you take peoples ideas (idea's have consequences) and take them to there fullest extent - it can have disastrous effect... In this case, you end up with simple minded individuals, who've used similar excuses and generalizations in the past to wipe out huge populations of the world such as Hutu-Tutsi conflict, Ethnic cleansing like Lenin, Mao, Hitler, Pol Pot. It's atrocious and absurd. Cancer is the enemy - not the human race. Not the innocent. Defeating cancer and reclaiming life is an absolute.
Please Keep Thinking - Please Keep Pursuing Life -
Remember - The Easiest Way Isn't Always The Right Way.
Merry Christmas!
Fox
Darwinists unite! The great news in this article is that cancer causes so many mutations! Our heroes Darwin and Devries would be ecstatic! Mutations are the key to evolution!
Don't cure cancer. It must be the cancers we've had for millions of years that has brought us to where we are...look how far we've evolved! It must be all these mutations. In fact, it looks like smokers are on the leading edge of the species! What a great idea - promote mutation within yourself for the betterment of the species!
Lung cancer can lead us to better lungs! Liver cancer to better livers! And the best, brain cancer to intellectual supremacy! (Am I running into Lamarck-ian problems with germ and somatic mix-ups here? No matter, mutation IS mutation you know!)
All you cancerous utilitarianists, take one for Team Humanity and let your cancer evolve the species!
(That's how it's happened for the past millions of years, right?) ...Am I going to get nailed for oversimplification here?
Well now I'm curious, some people's cancer metastasizes faster than other, while better yet, some people are genetically immune to type of cancer. So riddle me this? Why is there not more focus on individuals with cancer-immune genes and possible gene therapy for patience with fast-metastasizing cancers? That seems too simple.
Cancer affects everyone, no matter what walk of life you come from or what you believe. You live long enough, you're going to get cancer. It's just the cells breaking down and making bad copies. It's not one type of cancer is more important that the other. But I do agree collaboration will help between countries researching cures.
My hope is that treatment is not horded or hidden away from the public just because might get free health care. Won't that be fun when that picnic comes?
Most cancer paitents are old, and so a cure for cancer will only extend life by a decade or so. Yes, that will lead to an increase in the number of people living on the planet, but will have no affect on the increase of further generations, making it a limiting factor as life exspectancy increases.health questions answered
This is a great blog with lots of informative information about cancer. Keep up the good work! Also, please keep an eye out for my new Radon Gas blog: www.MitigationSystem.com - As I mentioned before, radon is the second leading cause of lung cancer. Over 8 Million U.S. homes have dangerous levels of radon gas (radon level of 4.0 or higher is dangerous according to EPA.) Learn more about radon testing and radon remediation at www.RadonMitigation.us or wait for my new post about radon abatement next week. Thanks for all of your help in this battle against radon and cancer.
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