“I honestly think people are more comfortable with the idea of nano-robots scurrying through their bodies than they are of deploying bacteria,” Thaler muses. “But when you think about it, you cultivate your lawn. You’d probably like to cultivate your internal landscape.”

Well said. After we can overcome the hurdles of human timidness toward the implementation of modified bacteria in our bodies, there seems to be an entirely open and new scope of research in terms of productive bacteria. Instead of trying to create new cures and treatments for age old problems, why not manipulate something already in existence and change harmful bacteria into helpful bacteria?

i think people are more willing to adapt than you think i my self think this is a very posible option for the future.

Once we understand the bacteria or virus genome, we could even reprogram them to hunt down other bacteria or viruses such as Flesh eating bacteria and HIV viruses. they can have a set lifetime of only a few days and have their reproductive genes removed or replaced.

The solution to all of humankind's problems is undoubtedly a natural one. Sunlight, modified bacteria, and algae are our friends. I know it sounds utopian, but seriously, we just need to make nature work for us in a symbiotic way. True, it may mean altering nature through genetic manipulation; but the point is that it can be done.

We have been talking in my Microbiology class about using viruses to carry the (gene manipulated) cure for diabetes; make the body produce it's own insulin again. This is the wave of the future for treatments. There is a huge potential benefit to gene therapy.

I was an AP biology teacher In 1993. Back then I asked a friend who was a doctor if some gut microbe couldn't be engineered to deliver insulin. He laughed. He said the naturally occuring bacteria are too well adapted to share space with a suboptimal organism. I countered that we could start with a patient's own flora, but he said simply adding or deleting anything would render it suboptimal.

In 1997 we attended a lecture on genetic medicine at the Exploratorium in San Francisco, the doctor was very sharp and forward-thinking. He said these avenues are "interesting but beyond our reach at present."

In 1999 my wife graduated with a B.A. in microbiology and almost every honor her university confers. Her signature position was that we view microorganisms the wrong way--a very small percentage are pathogens, while a large number are symbiotes--that we need to learn to work with them. Anyway, I asked her to mention my idea to her faculty. When she did, she was ridiculed by the full professors, tolerated by the more recent Ph.D.s, and taken quite seriously by the M.S. level instructors and graduate students. I'm gratified that she stuck with it long enough for us to learn that tenure often seems to impair the mind!

Fast forward to 2008. People are actually talking about my idea; while her idea is far more important. This plethora of Antimicrobial products not only threatens our personal micro-biomes, but it also accelerates resistance. These products should be tightly controlled lest we really do produce superbugs: PATHOGENS!

It's great if we can get friendly bacteria to do good things for us; it's terrible if we end up killing them off every time we use soap, toothpaste, lotion or even drink water!

Well, we do have one that eats oil spills then dies of hunger when the source is depleted... Sometimes there are some pretty cool successes.

Naturally our own bodies have bacteria that were not part of our makeup before that do all kinds of things symbiotically - not the least of which is digestion.

The concern is more like the problem in nature when a bacteria or virus gets in a mutated state that causes it to breed fast in a crowded environment and start causing disabilities and death. Don't think for an instant that a genetic 'bug' for good or ill will be the same for everyone, just like some people have large reactions to things like chicken pox and some people get killed by simple diseases on a wide scale.

Just some thoughts :)

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