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For the millions of people with intractable pain, Prialt offers 1,000 times the analgesic power of opiates but without the addiction and waning potency. The secret is a synthetic compound modeled after a paralyzing toxin made by a Philippine cone snail. Whereas opiates boost
pleasure chemicals, a catheter implanted in the spine delivers Prialt directly to nerve cells to block the transmission of pain signals to the brain.