Energy drinks, though, might be raising the stakes. "In the past it was generally accepted that it is virtually impossible for a normal, healthy person to consume a lethal dose of caffeine when taken in one of its usual dietary forms," James says. "Nevertheless, of the many thousands of cases of caffeine exposure registered with the American Association of Poison Control Centers alone, some do indeed result in death. Until the advent of energy drinks, essentially all of the many reports of lethal and near-lethal cases of caffeine poisoning, involved atypical methods of ingestion. The advent of energy drinks appears to have changed that profile."