The BLAST search didn’t come up with anything, but then the team, led by Glenn King of the University of Queensland, searched according to physical structure instead. They found it had a very similar shape to a hormone that helped spiders regulate their sugar metabolism, like the way insulin works in humans. Somehow over evolutionary time, the proteins that make up this hormone became weaponized, the researchers say. It may have had some adverse effect on prey, King theorizes. The researchers call this new structural class HAND toxins, for helical arthropod-neuropeptide-derived.