The more scientifically accurate the story is, the less fun the fiction.
Science fiction is a great genre, but science keeps showing up and explaining why the stories are unavoidably fictional. Have a great story about cloning dinosaurs in modern times? Turns out that DNA decays too rapidly for that to happen. Astronmers find canals on Mars and think they point to an alien civilization? Alas, not actually canals. Wait, but maybe there's life on Europa! Well, we'll have to wait until we shoot giant space bullets into the Europan ice to find out, but given the trend, it's still unlikely we'll find a teeming civilization beneath the surface.
This trend, of hyperbolic possibility countered by mundane reality, is ably mocked by the @HardSciFiMovies twitter account. Setting up a science fiction premise and then tearing it down all within the space of 140 characters, Hard Sci-Fi Movies provides a hilarious dose of reason in the fact of hysterical fiction. Hmmm, where have we seen that before?
Here are some of the best Hard Sci-Fi Movies tweets:
This could be anything from Dr. Jekyll and Mr. Hyde to Dr. Connors / the Lizard in The Amazing Spiderman. It's something of a trope.
This is pretty close to H.P. Lovecraft, especially the Mountains of Madness.