Jonathan Wyatt is less of a nuisance these days, his wife Diana told the BBC. Wyatt was the first volunteer to receive an experimental new gene therapy for a condition he has, choroideremia, that has slowly robbed him of his vision since he was 19. Two years after he received his treatment, he's able to read three more lines on the optometrist's chart. Diana Wyatt, of course, has other ways of measuring his improvement: "He is more independent, he can find things he couldn't before, he can go to the shops on his own and he's less of a nuisance!" she said.