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This almost reminds me, on second thought it does, of a certain anthrax researcher who killed himself recently, ostensibly, according to some reports, infecting others in order to give opportunity to prove the cure he was working on. I hope this works, but there are many signals to switch a defective gene on or off. In real life while there are genetic signals to turn something on, there are sometimes simultaneous signals to turn it off. Keeping that balance in perspective in the lab may be hard. If a person has a susceptibility for a genetic disease but environmental issues supply the trigger, then these tests may miss that interaction. It is a good approach, but certainly not a slam dunk. L Swinford Springfield, USA