vaccine

Stopping Influenza at Its Source

A half-decade study to track the flu's travels could lead to better vaccines

Flu travel patterns: Seasonal influenza strains typically emerge in Asia and spread to the rest of the world along the routes shown here.  Courtesy of NASA/University of Cambridge
Where does the flu come from? Scientists at the University of Cambridge and the World Health Organization's Global Influenza Surveillance Network tracked the migrations of flu viruses and discovered that the most common originate in East and Southeast Asia and spread in a distinctive pattern around the world. Understanding how these viruses evolve and travel will lead to better vaccines against flu epidemics that currently infect 5 to 15 percent of the world's population each year.

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Factory Farming and its Dire Consequences

The ills of factory farming reach beyond the ethical as immunologists grow increasingly concerned about a vaccine-resistant virus

One of the dire consequences of factory farming is that it encourages the spread of disease due to the close quarters in which the animals live. Thats why theyre fed antibiotics and other medicines when they arent sick. This overuse of antibiotics, while beneficial to the flocks and herds in the short term, leads to stronger and more drug-resistant bacteria in the long term. The effect has been widely reported by popular authors like Michael Pollan and Eric Schlosser. What we havent heard much about are how viruses can thrive in this environment.

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Vaccinations at a Tattoo Parlor

The most effective drug delivery system isn't a hypodermic needle

German scientists have demonstrated that the tattoo needle may be a more effective way of delivering vaccines than the standard injections. In tests on mice, the tattoo technique proved more successful in stimulating an immune response—tattooing a vaccine produced 16 times more antibodies in the mice.

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Flab in the Lab

A new way to lose fat, gain it, and even turn it into medicine

One-Shot Fat FixWant to fight fat? Eat less, exercise more-and get vaccinated. A fat vaccine is in the works at the Scripps Research Institute in La Jolla, California, where tests have led to leaner lab rats. The trick is blocking ghrelin, a hormone that slows down the body´s metabolism. The vaccine triggers the immune system to release antibodies that attack the hormone, enabling you to burn more fat. But don´t pass the holiday ham just yet. Human trials are several years away.

Hot ´n´ Heavy

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Pharming Underground

Can subterranean laboratories ease safety woes over crops that sprout medicine?

Don’t tell anyone, but Doug Ausenbaugh has built an underground drug farm—in bucolic southern Indiana, no less. It’s cleverly cached in an old limestone mine near the hamlet of Marengo. There, carefully cultivated stalks flourish under the glare of artificial lights and the rainlike spatter of drip irrigation.

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Just Shoot Me

A supersonic gun takes the ouch out of vaccine drug delivery

Take your medication with a gun made by PowderMed in Oxford, England, and the drugs will blast into your skin at 1,500 miles per hour. “You hear the sound, so you know it’s gone off,” explains Mark Kendall, a mechanical engineer at the University of Oxford and co-inventor of the flashlight-shaped disposable device.

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