
This advancement could save the lives of an unreal number of rats. First consider that the European Union alone has about 30,000 chemicals whose lung toxicities need to be tested within the next decade. For each chemical about 200 rats are needed to test the effects of a single dose. If chronic exposure is to be tested on that chemical, about 3000 are needed. Not only would these microlungs save countless animal lives, but it could streamline the drug development process by skipping the animal testing phase and experimenting directly on human tissue.
I’m sure rats everywhere are breathing tiny sighs of relief.
Five amazing, clean technologies that will set us free, in this month's energy-focused issue. Also: how to build a better bomb detector, the robotic toys that are raising your children, a human catapult, the world's smallest arcade, and much more.


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Ben "sighs"
Researchers at the University of Cardiff, UK, have already managed to grow human lung cells into flat differentiated layers that resemble the inner lining of the lungs. But when allowed to grow in three dimensions, as in the body, cells arrange themselves very differently, and this can change how they respond to chemical stimuli. A popular approach is to seed plastic scaffolds with stem cells to grow artificial 'organs.
But the researchers have found an alternative which could allow thousands of drugs to be screened at once. Instead of large scaffolds, they have grown lung cells on the surface of plastic spheres half a millimetre in diameter, essentially producing a tiny inside-out lung around each bead. The ultimate aim is to develop a chip on which
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