More often than not, it’s the newer diseases, like HIV or Ebola, that grab all the headlines. But those Johnny-come-lately microbes have nothing on one of the most dangerous, and most ancient, viruses that afflicts mankind: influenza.
Medicine has grappled with the deadly influenza virus since the time of Hypocrites, and some historians have identified flu epidemics as far back as ancient Rome. In a regular year, the Center for Disease Control and Prevention estimates that 36,000 Americans die from the seasonal flu, while the virus costs the nation between $71 and $160 billion. That’s ten times the death toll of 9/11 and double the cost of Hurricane Katrina, but it's far less noticeable, as the virus mainly kills the very old and very young, and the cost is spread out over the entire year in question.
Every few decades, though, the virus mutates into a particularly virulent strain, and spreads across the globe as a pandemic. While only the 1919 flu pandemic managed to create scenes reminiscent of the Decameron, the other pandemics have pried at the chinks in society, negatively impacting the economy and boosting the already high mortality rates for influenza. At the same time, some flu strains that were predicted to cause a pandemic never became as deadly as they were expected to, leading to accusations from the public that the media "hyped" virus' threat level. With the current swine flu epidemic continuing to expand, PopSci.com takes a look back at notable flu pandemics, as well as some threats that never materialized.
Check out the Gallery: Pandemics That Were and Weren't!
Five amazing, clean technologies that will set us free, in this month's energy-focused issue. Also: how to build a better bomb detector, the robotic toys that are raising your children, a human catapult, the world's smallest arcade, and much more.


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"Medicine has grappled with the deadly influenza virus since the time of Hypocrites"
There have probably always been hypocrites around - Hippocrates was the great Greek physician over 2000 years ago.
Anyway, I'd say in this situation its better to be a little over-cautious than not cautious enough, we are talking about possibly deadly epidemics. That's not to say some media outlets don't use the threat to gain viewership, but if they were right and their was a pandemic we probably wouldn't give them the credit they'd deserve.
Influenza is probably the most feared virus in the modern world. It can cause mass breakdown in communities and may kill the young and elderly. Yet, it is also a virus that we expect to receive each season. In recent year the preventative annual injections have reduced the severity, though scientists have not identified a cure for the humble and not so humble family of viruses
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