Reasons: They’re small and easily bred, and 99 percent of mouse genes (and likely rat genes too) correspond to human ones. Here, recent rodent-based research.
â€ Fighting AIDS and breast cancer
Investigators at UCSF made a mouse version of HIV, and a U. Wisconsin team created the first “knockout” rat; it was stripped of a gene that curbs human breast cancer.
â€ Extending the human life span
The Methuselah Mouse Prize promises $10 million for rejuvenating an old mouse so that it lives five years instead of three.
â€ Curbing depression
To test new antidepressants, French investigators bred “depressed” mice by selecting animals that don’t fight back when subjected to stress, such as being held by their tails.