This 1977 ad doesn't say exactly what's in the Total Contentment appetite-killing pill, but my money's on a whole lotta amphetamine. "So effective it helps shut off your appetite for hours at a time... instead of yielding to hunger... you simply reach for a pill instead."
At the bottom of the ad is a very sick, very sad box:
"VITAL NOTICE: You must promise to eat. Yes, even though the Total Contentment Pill has the ability to turn off your appetite just like you turn off a light switch, YOU CANNOT GO ON FOR LONG PERIODS EATING NOTHING... even though you have no appetite. Sure, you'd lose weight like crazy... but the doctor says it's unhealthy."
See the full ad here