Scientists at the University of Eastern Finland say they hope to have an allergy vaccine on the market in five to seven years.
For everything, from pollen to cat hair.
The antibody immunoglobulin E (IgE) works as the sneezy gatekeeper for allergies: it causes your white blood cells to release histamine, which in turn causes all of your favorite allergic responses, from a watery eyes to hay fever. Now, a team of scientists led by Professor Juhu Rouvinen have found a means of genetically modifying allergens so they won't bind with IgE, while still allowing them to interact with immunoglobulin G. IgG is the friendly cousin of IgE; it keeps allergies out by stopping the IgE-allergen complex from forming. That could block histamine from coming out of white blood cells, and thus block that runny nose. After that, it's simple, at least in theory: Just load a modified version in a shot and let the immune system take care of the rest.
Five to seven years might be a few too many springs away for allergy sufferers, but the team has formed a bio-tech company, Desentum, to help in production.
I am so sad. Poor Sneezy will have to find a new job from the Seven Drawfs. Waaaa!
Though, perhaps this will bring a new opprotunity to Sneezy and his health is no longer plague by allergies.
Yea, for Medical Science! Woo Hoo!
I wonder if this will work on food allergies also?
would this replace epi-pens?
even if it works it will never make it into production....fda only allows treatments, not cures.
Hey beefy, You ever missed out on something because you couldn't breathe, eat, see, smell, stop coughing, sneezing, snotting, gagging, cramping, crapping, convulsing, or throwing up? Prolly not. Even if was JUST a treatment, and only offered limited relief, it is a nice bit of news for people with bad allergies...
Unfortunately I have to agree with beefy. Pharmaceutical companies have a lot to lose if this vaccine materializes.
@Beefy, Klve & Apoc: I agree that the greedy pharmaceutical lobby in the USA won't want to let this get approved, but I think the people are now wise enough to exert pressure and to procure cures elsewhere. A trip to Mexico, Canada or even Finland doesn't seem too much of an expense to obtain a cure for a lifelong curse. Hope the Finns perfect it sooner rather than later.
How will they genetically modify all allergens? That makes no sense. Also changing the bodies reaction to the allergen from Th2 centered response to a Th1 could possibly mean the development of granulomas. Not enough explanation. Sounds improbable. Maybe if they created an antibody for IgE itself, although that has the potential for all sorts of other problems, not to mention the fact you wouldn't be able to fight helminth infections.
Most of the allergies are caused by vacines
Sam6302 obviously is not a scientist in any form...allergies have been around forever. Just a natural response that we can't help, it's known why it happens and there is no way around it, not due to vaccines by any means.
The FDA will never approve this! It would out drug companies out of business, there for is bad for economy, there for is bad for people, hence the FDA = NO GO on drug.
Because, that's just how it works in America.
Someone does something good, others say "we can't make money off of it" FDA says "ok. Drug not approved!"
I too, have an instinctive feeling doctors are more about treating symptoms, rather than curing people.
I also get a feeling, they much rather dispense a patented drug; verse a natural remedy with fewer side effects and lower cost.
I try to educate myself all the time on natural food, natural medicines and living a healthy life style.
My heart goes out to those who are sick. I do hope this medicine does help people of need.
I will forever worship these people like rockstars.
Research the benefits of Olive Leaf, Olive extract, Olive oil and olives.
Olive leaf is the leaf of the olive tree (Olea europaea). While olive oil is well known for its flavor and health benefits, the leaf has been used medicinally in various times and places. Natural olive leaf and olive leaf extracts (OLE), are now marketed as an anti-aging, immunostimulator and an antibiotic. Clinical evidence has proven the blood pressure lowering effects of carefully extracted olive leaf extracts. There is support its antibacterial, antifungal, and anti-inflammatory effects at a laboratory level. A liquid extract made directly from fresh olive leaves recently gained international attention when it was shown to have an antioxidant capacity almost double green tea extract and 400% higher than vitamin C.
The primary medical constituents contained in unprocessed olive leaf is believed to be the antioxidants oleuropein and hydroxytyrosol, as well as several other polyphenols and flavonoids, including oleocanthal.
Oleuropein preparations have been claimed for several pharmacological effects among them strengthening of the immune system.
After gallic acid, hydroxytyrosol is believed to be one of the most powerful antioxidants. Its oxygen radical absorbance capacity is 40,000 umolTE/g, which is ten times higher than that of green tea, and two times higher than that of CoQ10.
Oleocanthal has been found to be have anti-inflammatory and antioxidant properties. It is suggested that long-term consumption of small quantities of oleocanthal from olive oil may be responsible in part for the low incidence of heart disease associated with a Mediterranean diet.
Olive extracts have now been shown to function as anti-histamines at a cellular level. By blocking special histamine receptors (called H1 receptors), unique components in olive extracts may help to lessen a cell's histamine response. Because histamine is a molecule that can get overproduced in allergy-related conditions and can be a key player in the inflammatory process, it's likely that the anti-inflammatory benefits we get from olives involve this anti-histamine pathway. It's also possible that olives may have a special role to play as part of an overall anti-allergenic diet.
Good reading and source information of the Olive:
Oh thank Gawd
Did they say "genetically modifying allergens"? First, there's a lot of allergens out there, and it would take forever to modify them all. Second, there's no telling what ecological effects could result from that widespread intentional and sudden genetic alteration. Third, I'm pretty sure this is a misleading article, because it would make more sense to genetically modify our IgE to be less sensitive to alllergens, similar to ccr5 delta32, which makes humans immune to the most widespread forms of AIDS.