VBLOC by EnteroMedics EnteroMedics

In the 1980s, doctors noticed that chronic-ulcer patients who received a “vagotomy”—cutting the vagus nerve that controls the stomach—lost their ulcers and ended up with an intriguing side effect: They lost weight. The vagus nerve is the main route for signals between the stomach and the brain, regulating acid production, stomach expansion and satiation. Now medical companies are working on a pair of devices that modify these signals to help people with obesity.

The VBLOC, by EnteroMedics in St. Paul, Minnesota, is a small abdominal-cavity implant that blocks vagus-nerve signals by zapping the nerve with electric pulses. A similar implant, the Abiliti by IntraPace, based in Mountain View, California, sends additional signals instead of stopping them. The device electrically stimulates the stomach wall, which is thought to send a “full” feeling to the brain. Patients in VBLOC and Abiliti trials have shed, respectively, up to 30 percent and 38 percent of their body weight. Both devices could be on the U.S. market by 2014.

16 Comments

How about just teaching people to have self control, and to teach them to eat healthy, and how to exercise? The majority of the worlds people who are obese are NOT suffering from a disease or medical condition. If they are, then prove me wrong. Mind over matter. And yes, I realize that there are people out there who have conditions where they can't lose weight. It's a personal choice to eat Mcdonalds and those 10 chocolate chip cookiees.

Instead of making anti obesity devices, how about focusing on education and making fast food healthier or just eliminating it entirely.

So are you asserting that the reason there are so many obese people is because they don't know that eating less and exercising results in weight loss? I would counter that everyone knows this. It is a proven fact that most obese people have leptin resistance which causes their brain to not properly recieve satiety signals. If you don't believe this just google chemical signals and obesity. There are hundreds of documented medical articles about this.

I am not saying that obese people cannot lost weight through diet and exercise, but it is not the simple matter that you make it out to be. No one would choose to be fat if it was easily remedied.

Adding to what Cookie and jafonel said here. There are a lot of obese people who are so from depression, anxiety, boredom eating and other issues. The study here I bet does not take that into account at all. I see this as having the same issues as the current stomach staple surgery. Yes, weight is lost in the short term. However, in the long term that weight is almost always gained back. Unless the root problem of why the weight was gained in the first place, then something like this is only a short term bandaid.

There are also others that gain weight because of inability to exercise. I have a yet unexplained neurological problem in my low body that causes a severe stinging sensation from the waist down. An intense dull ache from fall to spring. I messed up back in the l4-l5 area. A problems with both wrists and my right shoulder that doesn't allow me to lift more then around 10 lbs and causes me to not be able to work above my head. As well as a few other issues.

Riding a bike (about the only thing I can do) doesn't do the trick. I don't see something like this working at all for people like me. Just changing signals without exercise wouldn't do much. I've already made meal adjustments and I've still gained around 40 lbs that I can't seem to shed.

Once we get past blaming everything else except ourselves then we might be able to wake up and get our nations health under control. Not everything is a "disease".

Remove added sugar of any type from foods, added fat, added salt, added colors and preservatives.

Legally force foods to be as close to the garden as possible.
………………………………………………….
3rd world countries do not have a problem with obesity.
USA and its clever manufacturing do have a problem.
..................................................

Well, this is my song and dance on eating better.
Learn the food pyramid, memorize it and eat as close to the garden as you can.
I am happy to pay more for quality food!
Seriously happy to do it, 'really really'!

Tell me grunt, how are you going to ship me oranges from Floridia, or keep all that food fresh from pick to sell, sometimess a week or more from field to table? Where are the local farms going to be around NYC for the massive pop there? Just curious......

lanredneck,
Guess what, I do not have the answer. But I do believe the factually the technology does exist and yes it would push up the cost of food. But I rather eat good food that watch all of USA be slow poison to death with diabetes, heart disease, cancers and more.

By the way, ever hear of refrigeration? I am sure you have and yes it requires electricity and more cost. I know and get that. But, I guess you prefer a chemical to keep you food fresh. Hell, that's your choice-enjoy. If you want to eat crap, go for it.

Making cheap food in USA is easy. But manufactures want profits and they will keep that food on the shelf as long as possible as you health expense and that is a real capitalistic fact!

let me assure you mind over matter people: Sugary and carbohydrate filled foods have a hugely addictive force on the brains of folks. In the same way cigarette smokers "need" cigarettes, some people "need" that pack of nacho chips.

yes, you can know that it's bad for you, and yes, you can try all you want to avoid it. but sometimes, it inescapable.

but the fact is, this shit our food factories are producing is addictive and the people who are fat are essentially junkies, jones-ing for the their next fix.

withdrawal from these substances can feel powerful and PAINFUL. and until you get your fix, just nothing will make you want to stop otherwise.

Food addiction is very hard to overcome. I struggle with it myself, having lost 100 lbs in the last year. but still occasionally having breakdowns in my ability to make the right choices, yes, even after a year, and all this success, it's still hard.

for people like me, moderation is not really an option. I need complete isolation from these products, otherwise, it turns into a feeding frenzy of once you pop, you can't stop. it's very hard.

i do however, believe that yes, it is a matter of self control. I just wanted to point out here that self control is something that some people have more or less of and willpower doesn't always win when compared to the ingrained programming of the evolved stomach, programmed for survival. Sometimes, I feel literally dragged to the cabinets, not by my mind, but by my stomach.

Eating the wrong foods, in excess, is the result of an addiction. You cannot put an addict in a room and tell them to eat just one. It's not going to happen. they'll try, but in the end, they're find a way to take and eat the whole bag.

Ways to control and manage this need to be explored further.

Education is not the answer. Really. We spend too much on education and we have yet to overcome any of mans faults by doing so. Continue research yes, but forget improving our character with it.

I find it interesting that there are those out there willing to say 'educate' people on food and exercise... Sometimes weight has nothing to do with will power or knowledge. Sometimes it has something to do genetics, an issue in body chemistry, (take a human grown and development class)or like in my case where it is an issue is pancreatic. I have insulin resistance caused because of a medical I have to take. I eat a low carb under 1600 calorie diet and still can't lose the weight I need to help fight my insulin resistance. I over produce insulin which my body isn't able to use. So anything that will help me lose weight is a good thing! So for those of you that take that whole attitude of 'people are just lazy and need to be educated' stuff it!

Genetics you say? Its a simple experiment really.
Lock a fat person in a cell and only feed them meals specially prepared by an expert dietician for six months.
I DARE you to stay fat!

@ killerT
Challenge accepted. 8 years ago I underwent major surgery. During the recovery time I was put on a very powerful non-anabolic steriod and was not allowed to be active. Over 6 weeks I put on 73 pounds eating only meals provided by a hospital.

In the years following I am still eating dietician supplied meals (my spouse is a certified nutritionist and dietician) and have managed to lose only 45 of those pounds. I am currently 225 pounds, run 3+ miles daily, have a daily caloric intake of 1800-2000 from a mostly vegatarian diet, and am still considered borderline obese. And this is 8 years later.

The steroids I was put on played havoc with my metabolism so technically no, it is not genetics, but it most certainly will not be rectified by locking me in a cell for 6 months and feeding me expert dietician supplied meals.

@Cookies453

You are forgetting depression and excessive amounts of stress. In the West we have both the luxury of abundant calorie sources and an abundance of sources providing distress(the bad kind of stress). We are also seeing more people suffering from broad ranges of depression than at any time in observable history, including some periods of natural disaster and pandemics that wiped out millions of people.

Most people who are morbidly obese actually know what they need to in order to solve the problem. The prevention usually comes from once you are that point, a person generally feels helpless to stop it or reverse it. This is obviously not the situation in all cases, but is shown to be the situation in more than half of them.

This is not simply an excuse, many studies from credible clinics and hospitals demonstrate this is a legitimate problem.

Part of the real solution would be to stop subsidizing bad crops that only exacerbate the problem, like corn and sugar cane. The other part of the solution is to tax the hell out of the production of fast food, it is a luxury item after all. Still another option would be to simply make it illegal as obesity rates have actually begun to threaten National Security.

In addition, we need to stop putting fast food restaurants in places labeled as "food deserts". We need to instead supplement, fortify, or provide local production and distribution of minimally processed vegetables, fruits, and meats in those areas. Minimally processed meaning no additives and only cleaning away what is absolutely necessary to get it from point of origin to market to customer.

I don't eat fast food, junk food or sweets, drink only occasionally, exercise 3-5 times/week, I'm an upper belt in Taekwondo, snowboard, bike, rollerblade and have decent cholesterol... but I'm technically obese; having a BMI of over 30%. I can lose weight with a very strict diet, but just going 500 calories over will cause me to gain weight. In addition, as an IT worker I sit most of the day, so keeping up enough motion to burn calories is tough and not really practical in my job. People who claim that anyone who is obese has no willpower, is lazy, uneducated or deficient in some other manner are themselves misinformed, ignorant and prejudiced (meaning you are prejudging people, not that you're a racist). This also didn't happen overnight, and the older you get, the harder it is to lose the weight.

My husband recently read this article and was facinated about the new information about the vagus nerve technology. Not so much for controling weight, but for possibly 'cracking the code' on our daughters odd eating challenges. She was born with some heart defects that were repaired at 8 weeks old. But we were told that the vegas nerve was damaged due to excessive stimulation while here her was swollen (for lack of a better medical definition). For her entire life, knowing when she is hungry has been a challege (understatement). She is very thin. She has suffered from behavior issues that go along with not having enough nutrition on board during the day. She does not know when she is hungry. Often, as a younger child if food wasn't visibly set before her, she would not eat nor ask to eat. We are grateful that she was able to survive her life saving surgery, but as she grows we are learning more about different 'side effects' from enduring the experience. Knowing that there could be a medical reason to what has been perceived to be a behavior issue brings a bit of peace. If there are any other parents out there with this same stuggle/epiphany we'd love to know.

Robert1234: Self control for obesity? man has been there, done that for about 250 years. Doesn't work for obesity, alcoholism, gambling, drugs, etc. Wake up people! Get your head out of the warm dark spot and THINK about reality of the world. We need REAL therapy that works, not right wing nuts making dumb comments about "self control". All that comment indicates is the writer isn't connected with real world reality.



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