Researchers at Stanford University just published a study in Nature that may give new hope to those looking to stop the effects of aging on the brain. The study found that when blood from a young mouse was injected into an older mouse, that older mouse enjoyed what could almost be termed a "rejuvenation effect": it began producing more neurons, firing more activity across synapses, and even suffered less inflammation.
Interestingly, performing the reverse, in which a young mouse was injected with blood (or, more accurately, plasma, which is the parts of blood without blood cells), resulted in young mice with distinctly elderly attributes--increased inflammation, a reduction in the production of new neurons, that kind of thing. The researchers used plasma because blood cells are actually too large to travel through the blood-brain barrier into the brain. But certain chemokines, small proteins secreted by cells, are indeed small enough to pass through, and the team actually isolated several that could be causing this effect.
It's a pretty fascinating study, as nobody had ever really believed that the degeneration of the brain with age could have been due to blood from elsewhere in the body, rather than merely a natural slowdown in the production of new neurons. The lack of new neurons can cause things like forgetfulness, specifically in spatial memory--forgetting where your car is parked, that kind of thing--so the ability to halt or reverse that process could mean amazing things for older people.
It may not make you live longer, but it's still a pretty amazing discovery.
[Stanford via Technology Review]
Five amazing, clean technologies that will set us free, in this month's energy-focused issue. Also: how to build a better bomb detector, the robotic toys that are raising your children, a human catapult, the world's smallest arcade, and much more.


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popsci if an elderly child murdurer comes out of the blue im blame ing you. because im sure some old person would KILL for rejuvination
______________________________________________________________
*growls*If you troll or flare I WILL MAUL YOU!*growls*
Well DUH! How do you think VAMPIRES live so long?? Geesh ... :P
If they can successfully clone a human in the future, would it be wrong to take the blood and or the spare parts of this youthful clone and use it for the older human?
The idea of this is rather creepy. I feel sad for the younger clone.
just dont clone the brain...
no brain = no person
bored? lets go mine the stars... ^^
So would this mean farming children's blood? Is there an age at which you can't give blood? (too young - bottom parameter)
@BubbaGump: I believe there was a movie made on that topic. and yes, it was very creepy.
why learn from your own mistakes, when you could learn from the mistakes of others?
Older men and Cougars are getting the same effect without a blood transfusion.
@BubbaGump I'm sorry but you ruin popsci, you add nothing of value to these articles at all. I know because I've been reading them for some time now. To be honest it puts me off reading knowing you'll be waiting at the end.
You often lead intelligent people down ridiculous parallels that would never happen in a million years and frankly it's a bore. Your comment on this article is a case in point. Please leave the commentary to people who at least appear to know what they're talking about.
Thank you.
P.S. Please refine your definition of the word troll. (This is not off topic, because you're the topic of my comment)
...then again, perhaps I'm guilty of feeding you. (That was a bit trollish)
hey, -my name here-,
"The Island" is the movie you're looking for.
Regards,
Marc Brown
Electrical Engineering Inventor/Programmer/Designer
Vale Varka Systems.com
Just don't clone Obama for god's sake.
Its seems all other comments are completely approved. lol
Way to go for extending the human lifetime!!!
I feel a song coming on....
Ben, the two of us need look no more
We both found what we were looking for
With a friend to call my own
I'll never be alone
And you, my friend, will see
You've got a friend in me
(you've got a friend in me)
Ben, you're always running here and there
You feel you're not wanted anywhere
If you ever look behind
And don't like what you find
There's one thing you should know
You've got a place to go
(you've got a place to go)
I used to say "I" and "me"
Now it's "us", now it's "we"
I used to say "I" and "me"
Now it's "us", now it's "we"
Ben, most people would turn you away
I don't listen to a word they say
They don't see you as I do
I wish they would try to
I'm sure they'd think again
If they had a friend like Ben
(a friend) Like Ben
(like Ben) Like Ben
Snif, Snif, this song is so special......
What about incentive programs for younger people to donate blood for older people i.e. college funding or something like that? I guess this whole issue might just be a slippery slope though.
@BubbaGump - WTF does that song have to do with anything? I hope you are happy that you are the most successful troll of all time, whether you are trying to be or not. You are indeed ruining PopSci comments sections.
@jcbullen, no need to cuss. I will explain sir.
"Ben" is a song written by Don Black and composed by Walter Scharf for the 1972 film of the same name (the sequel to the 1971 killer rat film Willard). Ben is a movie and song.
I saw the rat in the picture and my mind just traveled there. It does that. ..... I suspect I am older than you and I remember the movie and you do not.
FYI, in my life time I have donated over 3 gallons of blood on different random occasions of my life. I thank my Dear Lord for my good health and so donate to help others. Just a tiny little pain, can save several other people’s lives. Please be nice and donate, thank you.
@@BubbaGump you do realize your nothing but a f$$$ing troll (I know you know this because dozens of other users have pointed it out to you 2 JUST in this article).
I know you think you are cute, or being cute, and people want to read every single little thought that comes out of your brain, but we dont and guess what. your not nearly as clever as you think you are.
I wish the mods would do something about you.
I didn't know this website is called
BubbaGump's Popsci
out of 1000 users (estimated) you have 10% of ALL comments . you don't think thats a little over kill. branch out a little would you? there is more than one website out there.
most people post a comment a move on. you have to reply to EVERY single comment that you and someone else put then comment 3 more times on it. go back an look. some article you have 30% of EVERY comment posted. honestly you don't think thats a bit much?
Hey popsci admin: I am not going to come here anymore (and I am sure I am not the only one) because you have some extremely annoying users that think they can dominate the message boards with every little thought they think is funny or clever.
If you think he's a troll, I don't think you've actually met one yet. They're nasty.
While yes, there are a few posts that might not relate, but I guarantee there are more from people left ignored.
Also, some of his concepts hold merit. The average scientist today prefers lab experiments over thought, but thinking big and exploring the impossible is what gave us Einstein.
I should also, like to note, relating to this article:
People had ought to start recording statistics on the brains of people who've had blood transfer. This is one of the few human experiments we can morally do, because we already do the actions with little negative side effects.
pause for a moment ask a few questions. Do I have the power to stop any reader from commenting? Then ask how many readers read this website in your own imagination.
You make the opinion I post a lot, but is that really a true fact to the opprotunity of readers who could post a comment. What is the quantity of readers and why are they shy to make their own voice. There are hundreds of thousands of readers; why do they not make a voice? We are all anonymous.
To be fair, my voice is singular. I pray and wish OTHERS would stop and make a voice, opinion, a humor, an argument and just be interested!
I tell you something else, this particular website is respected and people of government read it. So in other words if common people wanted to influence their own government and make their opinions known about a particular science that comes up, THIS IS A WONDERFUL PLACE TO VOICE AN OPIONION!
The photo in this articles headline reminded me of a story from my grade school days, flowers for Algernon./
Very simillar, a bit of Sci-Fi tragedy. I enjoyed this article because it not only made me recall that story but also the time in recent history when life insurance companies recalculated their actuarial tables upward to age 120. At the time it seemed quite improbable. Now quite realistic. Science never ceases to amaze me. Recently a treatment has been devised for ALS & MS, I'm sure Dr Stephen Hawking is elated. Withy all the scientific discoveries much of what was science fiction is becoming reality.
I'm excited to be living in this age of discovery! What's next?
I vaguely recall similar studies being performed on monkeys. I believe they looked at muscle health. Does anyone know the names of these studies?
If I put high octane gas in my truck - it will run faster, hotter, and more "youthful" than it has in decades. That does not, however, mean that it is good for my truck. It will, in fact, hasten its wear and tear and eventual demise.
I would guess that youthful blood would have the same effect in an old body that should be working at a slower rate. Remember that the most active creatures (shrews, for example) have very short lives while slow/passive ones (giant tortoises, baleen whales, etc) have amazingly long lives.
Of course, there are always those who would trade ten good years for two great years.
Also, there is always a shortage of "young blood." That is why in the US there are always blood drives at high schools and why they let 17 year olds give (without needing parental consent for what is a medical proceedure, if a rather simple one). There are only a few years of adult sized body to give and young blood in the veins (by your mid 20's it has "grown up" with the rest of you). That means that only a few years of givers have to service almost two decades of patients, who, while small, often suffer from conditions that require a lot of blood transfusions (hemophilia, leukemia, etc).
LoL, such meanderings of triviality over the voice of science and reason, I implore, must be discontinued.
Hi, I just got back. I was watching this really cool movie.
Maybe you know it, "Nightmare on Elm Street", NICE!
Well, I just wanted to say good morning to everyone
and have a great day too. Bu-bye!
Lol, snort, Got-Cha!
are you serious
Did anybody READ the article? After looking in the blood PLASMA, they identified several chemokines (CELLULAR PROTEINS) that they believe to be the cause of the rejuvenation.
What does this mean for us? ENERGY DRINKS AND PILLS, that's what it means. Old folks can pop a daily pill to feel younger, and while you might not live longer because of it, you'll sure as heck feel better.
But that's not the extent of this research. Once they know the exact chemokines that cause this phenomenon, they can identify what cells make them and possibly why/how, and so this could lead to a huge leap in the advancement of the human life span. This is the kind of thing that makes science awesome!
(that's how to stay on-topic, people.)
BubbaChump just can't seem to control his loose bowels.
ew.....pltzzzz.... oh, sorry... stuff happens.
It's easy to tell real bubba from fake bubba. Fake bubba is literate.
@Jupiter1987, Sir, if you squeeze the fake bubba, only jelly comes out. The other bubba squeezed makes funny noises.... In identifying them, it’s all in how you squeeze the Charmin!
Just like a mosquito, it keeps coming back to annoy and enjoys it.
Never understood why if they do clone, not clone an entire body? Lets get to the point of having your dna stored and some stem cells with it. And whatever part you need, they just grow that part only from scratch. Might be awhile before we get there though...
And will someone shoot teh troll?
I like bubbagump. He is smart and has shown knowlegge on the matter at point. I am one of those readers-never writing guys, but the fact that he has risen so much controversy is a plus. Keep going Bubba!
Living to be 120 sounds like a good deal.
Sort of doubt that SS and my savings would last that long.
But maybe someone will simultaneously figure out how to feed all of us old antiques.
Surely technology will invent lots of new problems along with the new solutions to old problems.
Maybe a SS solution would be to receive "retirement" benefits from age 20 to 40, then work 'til you drop. The really dangerous jobs could be given to the over 90 group, with their "energizers" strapped on.
Regards