Scorpion venom and intense pain generally go hand in hand, but a group of researchers at Tel Aviv University are rethinking that relationship, using a better understanding of the peptide toxins found in scorpions' pain-inducing payloads to create a breed of non-addictive, side effect-free painkillers.
Pain is communicated to the brain via a certain type of sodium channel embedded in our nervous and muscular systems. Understanding the way these sodium channels convey the sensation of pain from certain parts of the body to the brain is key to manipulating these signals to reduce or eliminate feelings of pain. Figure out how to manipulate those mechanisms, and we could be on the way to a much less painful future.
Luckily for us, scorpions -- friendly little critters that they are -- have spent the past few million years evolving sophisticated toxins that can really turn up the level of excruciation. By modifying those same molecules, researchers believe they can customize compounds that are highly effective at numbing specific kinds of pain in specific parts of the body. What's more, because these compounds are natural and tailor-tweaked, they can be engineered to perform without side effects like addiction or the state of lovely but intoxicating loopiness induced by other painkilling compounds like morphine.Therein lies the benefit, of course; anyone who's had wisdom teeth pulled or dealt with a serious ligament tear knows that a bottle of conventional pain meds can get the job done, but the side effects can be mentally impairing and even dangerous should one become chemically dependent. With bio-mimicking pain compounds, doctors could treat chronic discomfort without fearing that patients might end up in the streets trying to score that next hit of scorpion.
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"What's more, because these compounds are natural.."
Nothing chaps my behind more than the whole Natural = Good and Synthetic = Bad view of the public at large. Plenty of "natural" compounds are lethal so just because something is "natural" DOES NOT MEAN IT IS AUTOMATICALLY GOOD FOR YOU! I would like to think that websites like this one would know the difference instead of perpetuating a myth.
Rattlesnake bites are natural...
Volcanoes are natural...
Malaria is natural...
Hemlock is natural...
AIDS is natural...
Hungry lions are natural...
Natural stuff is dangerous!
Weren't they thinking about doing the same thing with the venom of a sea snail that killed and ate fish? It's venom is supposedly non-addictive and 1000% times more efficient than morphine. I read that article a few years back.
Oh yeah, it's natural, too!!!!
"What's more, because these compounds are natural and tailor-tweaked, they can be engineered to perform without side effects like addiction or the state of lovely but intoxicating loopiness induced by other painkilling compounds like morphine."
Morphine is a natural compound. If one smokes an opium poppy, they are getting high mostly off of morphine, as well as other opioids.
Furthermore, heroin is a "tailor-tweaked" form of morphine and is also much more addictive than morphine. This article completely ignores the fact that tweaking natural compounds can also lead to deadlier, more addictive chemicals, not just the other way around.
the dead certificate now says (scorpion sting scratch off)...."Dead by NATURAL causes"
God you people are negative. Maybe you would all be happier living in the Dark Ages. Matter of fact maybe if we stop testing and advancing new medicines all together you will be happy. Matter of fact maybe we should just stop all scientific advancement all together. I hate negativity.
First, as another pointed out, opiates are natural, though some have been meddled with. Also, what no one seems to notice is that, first, when opiates are taken for pain, the molecules, the same as the endogenous opioids made by the body, combine with receptor sites, and while the "loopy" effect may continue for a few days, at most a week, they don't last. Also, chemical dependency happens with a LOT of other drugs as well. All it means is that your body has ceased to make a natural substance because you've been replacing it with a similarly-functioning substance from outside the body - that means you get withdrawals. It's strictly biochemical, and has nothing to do with addiction, which is a phychobiochemical phenominon. Addiction actually occurs only in the 1%-3% or even less, sometimes much less, of the population that is predisposed toward it, and it's related to obsessive-compulsive disorder. Using opiates, even in very high doses, doesn't mean you will become addicted, and even addicts need pain relief sometimes, which can be done with the correct precautions.
Chronic pain afflicts 75 MILLION Americans, and because of an out-of-control DEA (abetted by an out-of-control DOJ and sometimes by Bush-appointed federal judges), almost ALL are under-treated or entirely untreated. Chronic pain causes terrible damage, and even acute pain - like from an operation, or slamming you hand in a door - pain that will go away soon - should be treated much more aggressively than it is. Post-op patients whose pain is treated right heal more quickly, complain less, sleep and eat better and have better outcomes. Older patients are far less vulnerable to delerium as well if their pain is treated.
An estimated 20,000 people in pain take their own lives every year for lack of pain control because the DEA has tried to turn doctors into cops, and has also railroaded over 400 of them into prison for following the Medical Standard of Care as well as the law. The drug warriors ignore both. And the government propaganda, like here, is thought to be truth, and it never stops.
Lastly, if this works, it will be because it hits the opiate receptors in the dorsal horn of the spine where pain is mediated and does the same thing, so it will be like taking any other opiate.
Ian
because they are tampering with its chemical structure, it isn't entirely natural now, is it
Nutra Pharma has already completed and is awaiting the use of THEIR pain relieving products by those in the medical profession.
THEIR product needs NO 'further' testing and is ALREADY on the market.
"Their current drugs are derived by modifying the venom and toxin of snakes"
This is such a good idea. Its amazing what technology is at today.
________________________
Jocelyn Ma
http://www.bodymagicshaperreviews.com/
Do not be too sure that scorpion wont find its way on the streets. I even go as far as saying the drug is being developed alongside this development. Scorpion, as a name, has a good street ring to it. The chemists who manufacture illegal street drugs use many medications to produce a range of mind altering effects. This could be the next big movement on the street.
www.backpainandrelief.com
God you people are negative. Maybe you would all be happier living in the Dark Ages. Matter of fact maybe if we stop testing and advancing new medicines all together you will be happy. Matter of fact maybe we should just stop all scientific advancement all together. I hate negativity.
God you people are negative. Maybe you would all be happier living in the Dark Ages. Matter of fact maybe if we stop testing and advancing new medicines all together you will be happy. Matter of fact maybe we should just stop all scientific advancement all together. I hate negativity.
www.tran33m.com/vb