tumors

Transforming surgical scalpels into imaging tools could provide instant feedback on suspicious tumors or tissues. European researchers plan for the new imaging tools to enter clinical trials next month.

The concept combines an elecroscalpel with a mass spectrometer to profile the molecular structures of whatever the scalpel happens to cut. It carries out its molecular analysis by using "surgical smoke," or gaseous ions produced as a waste product of the electroscalpels, which requires removal anyway during surgery.

Chemotherapy is notorious for the toll it takes on the entire body. It kills cancer cells, sure, but it kills a lot of healthy cells, too. But soon a new advance in carbon chemistry may replace the shotgun blast of chemo with a radiation sniper shot.

When your mother says eat your greens, you just might want to listen. It's been known since the 1970's that cruciferous vegetables, or cabbage family vegetables, such as broccoli, cauliflower, Brussels sprouts and kale, have anti-cancer benefits. But researchers at the University of California, Berkeley, who have studied the benefits of anti-cancer vegetables for 15 years, are the first to explain how an anti-cancer compound, indole-3-carbinol (I3C), found in broccoli and cabbage, works to slow down the activity of an enzyme linked to rapidly developing breast cancer.

“Cancer treatments have hit a wall,” says chemist Michael J. Sailor of the University of California at San Diego. Today’s chemotherapy drugs leave the body too quickly, and both chemo and radiation kill healthy cells indiscriminately, he explains. So he has developed “nanoworms,” strings of iron-oxide particles that could swim through your blood to kill nascent cancerous tumors—and nothing else.

Its a drizzly morning on New Yorks Upper East Side, and Rockefeller University microbiologist David Thaler is sipping a double espresso amid the retro-hippie pillows and dangling paper stars of Java Girl, a favorite haunt of the neighborhoods brainiac Nobel laureates, aging poets and famous entertainers. Thaler somehow manages to embody all three—a long, graying ponytail curling down the middle of his back, wire-frame glasses askew over expansive brown eyes, and a schnozz to rival an Einstein, Ginsberg or Allen. Thaler is one of the leading cheerleaders for a new field of biotechnology aimed at engineering the bacteria inside us to deliver drugs, destroy tumors, actively fight infection, and even vaccinate against their disease-causing kin.