rodents

A group of leading researchers working on hearing loss have created mice whose hearing worsens as they age, as mirror counterparts to humans. But these mice fail to breed well, which led the University of Rochester group to crossbreed them with mice that had great sex drives but even worse hearing loss in their old age. The result was a new super breed that is prolific and has superb hearing.

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Naked mole rats are unique in many ways. For one, they're the only mammals with a hive mind, obeying their queen as if they were ants. Also, they feel no pain, an adaptation still not fully understood. But most importantly for us, they are the only animals that don't get cancer.

And now, a new study by scientists at the University of Rochester, New York, explains at last why these horrific animals, of all of the world's creatures, are immune to cancer.

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In this video, a mouse runs through a virtual maze derived from a Quake 2 level, by steering a trackball suspended on a jet of air. Obviously the Princeton scientists did this because it's awesome, but the ostensible reason is because it gives them unprecedented access to study the neurological activity of the rodent while it moves around.

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Forget the Orkin Man; with pests like this, you might need to call Ripley. Scientists have recently discovered two new, giant versions of common pests.

In this corner, hailing from Papua New Guinea and weighing in at a hefty 3.3 pounds comes the the Bosavi woolly rat. And in the other corner, in the bright yellow outfit and representing Malaysia, please welcome Heteropoda davidbowie, "the Spider from Mars."

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Head Tilt Mouse

Ever since Mario Capecchi, Martin Evans, and Oliver Smithies created the first knockout mouse in 1989, genetically engineered animals have steadily increased in popularity for all kinds of biology research: simply pick a gene, turn it off in the mouse, and see what happens.

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Just the sound of a dentist's drill is enough to send most people into a panic. Add to that the awful inconvenience of walking around for a day with half your face numb, and it's easy to see why getting a cavity filled or a tooth replaced is one of life's most annoying chores. Fortunately, some new research may make the common drill-and-fill a thing of the past.

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The next time someone tries to argue that all M&Ms are the same, no matter the color, you can tell them about the blue M&M. The candy (like Gatorade and other products) gets its color from a food dye similar to Brilliant Blue G (BBG) -- a compound that, as it turns out, is medically useful. Building on earlier research, scientists at the University of Rochester Medical Center have found that injections of BBG can relieve mice of secondary spinal cord injuries. In September, they will start conducting human clinical trials.

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Chinese scientists have created live mice from mature skin cells that had reverted to an embryonic-like state. The scientific success could further defuse controversy over harvesting embryonic stem cells, but also raises new ethical issues about potentially making clones selected for specific traits.

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Four years ago, a team of researchers at the École Polytechnique Fédérale de Lausanne in Switzerland switched on Blue Brain, a computer designed to mimic a functioning slice of a rat's brain. At first, the virtual neurons fired only when prodded by a simulated electrical current. But recently, that has changed.

Apparently, the simulated neurons have begun spontaneously coordinating, and organizing themselves into a more complex pattern that resembles a wave. According to the scientists, this is the beginning of the self-organizing neurological patterns that eventually, in more complex mammal brains, become personality.

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