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How to heal an infection that defies antibiotics? Another infection. Doctors in Eastern Europe have used lab-grown viruses to safely cure millions of wounds. So why can't we do the same here?

It seemed like nothing at first. The red patch that appeared on Roy Brillon's thigh could have been a spider bite. But as the weeks passed, it grew and grew. By December 2004, the innocuous-looking bump had become an open wound the size of the palm of his hand. Brillon's doctor, Randy Wolcott, prescribed just about every antibiotic he could think of to cure the infection, but the lesion just got worse. "It was really bad," says Brillon, a 62-year-old retired housepainter from Lubbock, Texas. "I had to give up work because I couldn't climb ladders anymore."

Brillon felt like he was being eaten away from the inside out. And in a very real sense, he was.

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