human life span

Fountain Of Youth Found On Easter Island?

Compound found on Easter Island shown to make mammals live longer

Rapamycin, a compound originally found in Easter Island's soil in the 1970s (right there under the stone heads) has recently been proven to extend the lives of mice.

When tested on mice that had already reached middle age, the subjects treated with rapamycin increased their lifespan by 28-38 percent. Scientists are identifying these studies as the most promising drug-induced technique for increasing longevity, which is generally possible only via genetic manipulation or limiting caloric intake.

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The Warp Drive

In a rush to flee the solar system? Scientists have an interstellar travel plan, but it entails a brief stint outside the known universe

What: A spacecraft that travels at faster-than-light speeds by distorting, or "warping," the fabric of spacetime. Instead of trying to move through space, the warp drive moves space itself. The ship sits inside a bubble of spacetime bound by a negative energy field that races across the cosmos.

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The Prophet of Immortality

Controversial theorist Aubrey de Grey insists that we are within reach of an engineered cure for aging. Are you prepared to live forever?

On this glorious spring day in Cambridge, England, the heraldic flags are flying from the stone towers, and I feel like I could be in the 17th century—or, as I pop into the Eagle Pub to meet University of Cambridge longevity theorist Aubrey de Grey, the 1950s. It was in this pub, after all, that James Watson and Francis Crick met regularly for lunch while they were divining the structure of DNA and where, in February 1953, Crick made his breathless announcement that they had succeeded.

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They Die by the Score

No creatures make more sacrifices for science—albeit involuntarily—than the mice and rats of lab research. Some 30 million are used each year in the U.S. alone.

Reasons: They’re small and easily bred, and 99 percent of mouse genes (and likely rat genes too) correspond to human ones. Here, recent rodent-based research.

†Fighting AIDS and breast cancerInvestigators at UCSF made a mouse version of HIV, and a U. Wisconsin team created the first “knockout” rat; it was stripped of a gene that curbs human breast cancer.
†Extending the human life spanThe Methuselah Mouse Prize promises $10 million for rejuvenating an old mouse so that it lives five years instead of three.

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Homage

They die by the score.

No creatures make more sacrifices for science -- albeit involuntarily -- than the mice and rats of lab research. Some 30 million are used each year in the U.S. alone. Reasons: They're small and easily bred, and 99 percent of mouse genes (and likely rat genes too) correspond to human ones. Here, recent rodent-based research.



Fighting AIDS and breast cancer
Investigators at UCSF made a mouse version of HIV, and a U. Wisconsin team created the
first "knockout" rat; it was stripped of a gene that curbs human breast cancer.



Extending the human life span

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December 2009: Best of What's New

In our December issue, Popular Science names the 100 best innovations of the year: bombproof wallpaper, self-parking cars, the fastest helicopter, and 97 more. Plus inventor profiles and videos.

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