health

Nanoparticles Can Damage DNA Without Crossing Cellular Barrier

Metal nanoparticles use a newly observed cell signal process to wreak havoc indirectly

Scientists know that nanoparticles can damage DNA in cells through direct interaction. Now, though, it appears that nanoparticles can also mess with DNA on the far side of a cellular barrier, by creating signaling molecules -- a never-before-seen phenomenon.

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Mutant Bacteria Are Likely to Threaten Future Space Travelers


When humans eventually travel to Mars and beyond, they'll have plenty to worry about along with the discomforts of eating freeze-dried food and drinking their own urine. A new report says they will probably be really sick, to boot -- from flare-ups of E. coli, chicken pox or staph infections.

A host of microscopic stowaways could make interplanetary voyagers sick, especially because human immune systems are compromised in space, and because bacteria seem to thrive in micro- or zero-gravity environments.

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Will a Shortage of Nuclear Isotopes Mean Less Effective Medical Tests?


The Chalk River nuclear reactor in Ontario doesn’t sell a watt of electricity. Never has. But when it sprang a leak and shut down this spring, it threw a multibillion-dollar industry into crisis. Before it broke, the reactor produced nearly two thirds of the U.S. supply of molybdenum-99, or Mo-99, the isotope behind 16 million critical diagnostic medical tests each year. In July, things got worse: The Dutch reactor that supplied the remaining third shut down for a month of repair work.

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Tiny Thermoelectric Loudspeaker Produces Audio By Tweaking Temperature


A standard home audio speaker converts electrical signals into sound pulses in the air (via a somewhat cumbersome cone). Those sound waves in turn cause tiny variations in air temperature, as waves disrupt surrounding air. So, scientists reasoned, why not create sound waves through those temperature fluctuations themselves?

In 2008 researchers built a loudspeaker from carbon nanotubes that creates sound from this thermoacoustic effect. Now Finnish researchers have created a far more simple thermoacoustic device using tiny aluminum wires suspended over a substrate, opening thermoacoustics to a far broader range of applications.

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Silk-Silicon Implantable Electronics Conform to Tissues, Then Melt Away


Implantable electronics like pacemakers are old hat, but these kinds of implants are limited by the fact that they must be encased to protect them from the body, and vice versa. But in the quest to make our bodies ever more bionic, researchers have now developed implantable silicon-silk electronics that almost dissolve completely inside the body, leaving behind nanocircuitry that could be used for improved electrical interfaces for nervous system tissues or photonic tattoos that display blood-sugar readouts on the skin’s surface.

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Lawsuit Banning Human Gene Patents Continues, Court Rules


The ACLU is one step closer to getting patents on human genes banned after a federal court today ruled that its lawsuit can continue. The defendants (The US Patent and Trademark Office and the owners of the BRCA breast cancer gene patent) had asked the court to dismiss the case.

About 20 percent of the human genome is currently patented, including genes associated with many diseases such as breast cancer and Alzheimer's. The patents mean that outside researchers need permission to study the genes and that tests can be astronomically expensive. (The test for BRCA is about $3,000.)

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California Launching Massive Genetic Health Database

Researchers can access a treasure trove of genetic analyses from 100,000 elderly Californians

A new genetic database for 100,000 elderly Californians is slated to come online within two years, and marks the first time that genetic data becomes available for such a large and diverse group.

Health-care provider Kaiser Permanente will hand over patient data that includes electronic health records, lifestyle surveys, and info on air and water quality in patients' neighborhoods. The effort draws on $25 million from the National Institutes of Health, and also involves researchers from the University of California, San Francisco.

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For the First Time, Geneticists Diagnose Disease Through Whole-Genome Analysis


For the first time, researchers have made a clinical diagnosis by sequencing the entire protein-coding parts of a person's genome.

"We have shown that one can use whole genome sequencing to make clinically meaningful diagnoses- it is technically feasible . . . and can provide new clinical insight that directs treatment," Richard Lifton, a geneticist at Yale who spearheaded the research, told Popsci.com.

Protein-coding DNA only makes up about one percent of the human genome, but is responsible for about a large portion of diseases with a genetic component.

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Placebo Effect's Neural Activity Photographed for First Time

Researchers used fMRI scans to spot the placebo effect at work in specific spinal cord cells

Medicine has increasingly looked to the placebo effect's seemingly mysterious power to make people feel better in the absence of painkillers or pharmaceutical drugs. Now researchers have used fMRI scanners to pinpoint specific cells in the spinal cord that they believe are responsible for this ability to deaden pain.

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US Special Forces Field-Testing Plasma Knife


Emergency medical care for soldiers wounded on the battlefield has come a long way since Hawkeye and Hot Lips. But for Special Forces troopers operating deep behind enemy lines, that care often remains out of reach. Blood loss in particular makes seconds count, and imperils commandos operating far away from friendly bases.

To help with the problem of blood loss from traumatic wounds, the military has started field-testing a device more Mandalorian than M.A.S.H.: a plasma knife.

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November 2009: Astronaut 3.0

Inside NASA's astronaut bootcamp and the grueling new training regimen for deep space. Plus, ten young geniuses shaking up science today, one writer's quest to analyze every man-made chemical in her body and more.

Check out the issue's full contents online here

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