Tired of car chases, robberies, and general action-packed anarchy? Set aside Grand Theft Auto IV for a minute and enter a new kind of gaming adventure: the exciting world of protein folding! Researchers at Howard Hughes Medical Institute and the University of Washington have developed Foldit, a free, online game in which players compete to design proteins.

SETI@home—part of the Search for Extraterrestrial Intelligence—is one of the earliest successful distributed computing projects. Its intent is to discover the presence of extraterrestrial life by analyzing radio signals from deep space. I remember the excitement of joining in late 1999, watching the candy-colored bars make their way across the client screen as my computer worked to detect meaningful variations in the cloud of noise. SETI has not yet been successful—that would be pretty big news—but the distributed computing model that has come out of it has.