disease

On May 5th, Konan Michel Yao was arrested for smuggling vials from a Canadian ebola research center into the United States. However, Mr. Yao wasn't a terrorist attempting to commit a biological weapon attack. Instead, Mr. Yao was a government scientist, en route to his new job studying biodefense at the National Institutes of Health. Additionally, he didn't even have any ebola in his possession.

More often than not, it’s the newer diseases, like HIV or Ebola, that grab all the headlines. But those Johnny-come-lately microbes have nothing on one of the most dangerous, and most ancient, viruses that afflicts mankind: influenza.

The hardest part of writing about the swine flu outbreak has been striking the right tone. No doubt, this is a serious threat, as even a mild flu pandemic, on the order of the 1968 Hong Kong flu, would cause significant economic downturn at a time when the country already faces immense financial problems. On the other hand, hyping the threat does a disservice to the very public that the media intends to help.

It's been three days since swine flu made it to the front page of most newspapers, and I'd like to thank all the readers who have chosen to follow PopSci's coverage, instead of retreating to their basements with ammo and clean water. Here are some highlights from the ongoing media frenzy.

And now some good news to end the day. This afternoon, after the US Center for Disease raised the number of swine flu cases in America from 20 to 40, the World Health Organization (WHO) raised the pandemic threat level from three to four, out of six. Level four means the virus has been observed transferring from human host to human host without an animal intermediary, and is the final step before the WHO declares a pandemic underway.

With officials testing 17 people in Spain for swine flu infection, the European Union's (EU) health commissioner warned Europeans to steer clear of Mexico and the United States if possible. However, the acting Director of the U.S. Center for Disease Control and Prevention (CDC) told CNN that a travel advisory may be premature.

Over the weekend, health officials around the world shifted into high gear as a deadly strain of swine flu began working its way around the globe. On Saturday, the Center for Disease Control (CDC) issued a health advisory about the flu, while the World Health Organization (WHO) held an emergency meeting, declaring that "current events constitute a public health emergency of international concern."

When it comes to viruses, especially the serious kind that can make you bleed from your eye sockets and wipe out entire villages, most people naturally prefer to keep their distance. Not Nathan Wolfe. The 39-year-old epidemiologist has spent the past 10 years hunting them down in the jungles of Southeast Asia and sub-Saharan Africa. By collecting thousands of blood samples from wild animals and the people who live in close contact with them, Wolfe and his team have uncovered new viruses related to HIV and smallpox. He's even documented how these animal-borne killers leap to humans, with blood serving as a vector in transmitting viruses from slaughtered animals to hunters.

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The pandemic has hit. The flu has infected millions of people, civilization is on the brink of collapse and there’s only so much vaccine to go around. The plan calls for saving the most vital members of society, the ones who can help save us from the plague. The plan says vaccinate doctors. The plan is wrong.

One can hardly fathom the horror of life in the Congo Free State during the turn of the last century when native Africans suffered genocide at the hand of Belgium’s King Leopold II. In those conditions, no one would have noticed people dying of a strange disease that would not be named for another hundred years. No one would have noticed people dying of AIDS.

For years scientists have been touting a disease-fighting technique called RNA interference. The idea behind it is pretty simple: By piggybacking on the body's own system for silencing genes, researchers think they could stop troublesome proteins from being produced, and, as a result, halt the damage those proteins cause. The trick, though, is that scientists have had a hard time figuring out how to make RNAi, as it's known, work on specific tissues.

University of Florida scientists have developed a new gadget that basically annoys patients into taking their prescribed drugs, then tests their breath to ensure that they've actually swallowed the necessary pill. When it's time to take your medication, the machine beeps. Ignore it and it beeps again. In fact, it gets louder and louder until you actually respond—after a predetermined time, if you haven't swallowed your meds, it sends a message to the clinical trial coordinator. The device also performs a breath test that picks up the presence of a chemical tracer.