disease

Mutant Bacteria Are Likely to Threaten Future Space Travelers


When humans eventually travel to Mars and beyond, they'll have plenty to worry about along with the discomforts of eating freeze-dried food and drinking their own urine. A new report says they will probably be really sick, to boot -- from flare-ups of E. coli, chicken pox or staph infections.

A host of microscopic stowaways could make interplanetary voyagers sick, especially because human immune systems are compromised in space, and because bacteria seem to thrive in micro- or zero-gravity environments.

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For the First Time, Geneticists Diagnose Disease Through Whole-Genome Analysis


For the first time, researchers have made a clinical diagnosis by sequencing the entire protein-coding parts of a person's genome.

"We have shown that one can use whole genome sequencing to make clinically meaningful diagnoses- it is technically feasible . . . and can provide new clinical insight that directs treatment," Richard Lifton, a geneticist at Yale who spearheaded the research, told Popsci.com.

Protein-coding DNA only makes up about one percent of the human genome, but is responsible for about a large portion of diseases with a genetic component.

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Feature

Instant Expert: the Return of Swine Flu

The Big Question: How many people will it infect this year?

Flu season in the Southern Hemisphere is almost over—and now it’s heading back our way. At the time this issue went to press, there were more than 162,000 confirmed cases and 1,154 deaths worldwide from “novel H1N1,” a.k.a. swine flu, but the Centers for Disease Control and Prevention believes this figure is a gross underestimate, especially since only a fraction of people who have the flu go to the hospital.

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AIDS-Like Virus Threatens Koalas With Extinction


A decade ago, the bells of doom started to sound for carefree, swinging koalas. A new, HIV-like retrovirus had begun to attack the koala population, decimating its ranks and threatening extinction.

Now, the Australian researchers have launched an effort to stop the spread of the virus before it's too late.

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Tested: Fighting The Great Flu Pandemic Online


A game called The Great Flu, developed by virologists at Erasmus Medical Center in Rotterdam, lets you unleash the flu virus of your choice on the world, then use your $2 billion budget to contain it through a palette of public health moves.

Playing it, I've certainly gained a little knowledge about the flu and a lot of empathy for the WHO.

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In New Trial, Mosquitoes Spread Malaria Vaccine


Malaria kills upwards of a million people a year, infects hundreds of millions, and significantly damages the economies of dozens of countries. Cures and prophylaxis for malaria range from bug nets to drugs to gin and tonics, but none are weirder -- or more poetically just -- than a new method that uses mosquitoes themselves to deliver a malaria vaccine.

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Are We Unintentionally Breeding Hordes of Killer Super-Animals?

Unstoppable mutant vermin and farm critters stir up health scares

This Little Piggie Had Ebola

In January, the Ebola virus leapt from pigs to farmers in the Philippines. Butdon't panic. Despite being a cousin of the deadly African strains, this one, Ebola-Reston, merely causes flu-like symptoms in humans, says Pierre Rollin, a biologist at the Centers for Disease Control and Prevention. To be safe, the Philippine government ordered farmers to euthanize 6,500 pigs from infected farms. Ebola-Reston was first seen in Philippine monkeys in 1989 and has since passed to other species. Scientists think contagious bats urinated in pigs' water supply, and the swine then coughed the virus onto humans.

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Rats' Neighborhood Pride Has Implications for Epidemic Control

A new study finds that city rats have their own neighborhoods

When the words "Baltimore" and "rat" appear together, they usually involve a discussion of the fate of The Wire's Wallace or a DVD featuring Carmelo Anthony. However, unlike the alleged turncoats, it seems that actual rodents really do hold down their block. According to a new study in Molecular Ecology by a team of Johns Hopkins scientists, Norwegian rats are as neighborhood-oriented as any of the bipedal residents of Charm City.

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Researcher Charged With Smuggling Stolen Ebola Virus

... despite the fact that he did not in fact have any of the virus with him

On May 5th, Konan Michel Yao was arrested for smuggling vials from a Canadian ebola research center into the United States. However, Mr. Yao wasn't a terrorist attempting to commit a biological weapon attack. Instead, Mr. Yao was a government scientist, en route to his new job studying biodefense at the National Institutes of Health. Additionally, he didn't even have any ebola in his possession.

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Pandemics That Were And Weren’t

After a week of swine flu hysteria, PopSci.com takes a look back at the history of pandemic flu

More often than not, it’s the newer diseases, like HIV or Ebola, that grab all the headlines. But those Johnny-come-lately microbes have nothing on one of the most dangerous, and most ancient, viruses that afflicts mankind: influenza.

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December 2009: Best of What's New

In our December issue, Popular Science names the 100 best innovations of the year: bombproof wallpaper, self-parking cars, the fastest helicopter, and 97 more. Plus inventor profiles and videos.

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