david thaler

This Germ Could Save Your Life

Or at least keep your teeth cavity-free. A growing chorus of medical researchers say our bacteria-killing zealotry is misguided. Instead of fighting bugs, they argue, we should train them to do our bidding and then set them loose in our bodies. The trouble is keeping them there

Its a drizzly morning on New Yorks Upper East Side, and Rockefeller University microbiologist David Thaler is sipping a double espresso amid the retro-hippie pillows and dangling paper stars of Java Girl, a favorite haunt of the neighborhoods brainiac Nobel laureates, aging poets and famous entertainers. Thaler somehow manages to embody all three—a long, graying ponytail curling down the middle of his back, wire-frame glasses askew over expansive brown eyes, and a schnozz to rival an Einstein, Ginsberg or Allen. Thaler is one of the leading cheerleaders for a new field of biotechnology aimed at engineering the bacteria inside us to deliver drugs, destroy tumors, actively fight infection, and even vaccinate against their disease-causing kin.

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