cell biology

First Hi-Res Picture of a Virus's Shell

Scientists create an image of the five-million-atom-large capsid

Handle with Care: To protect itself, a virus like the one shown here uses a protein shell to seal off its genetic payload  J. Tao and J. Pan (Take a closer look!)

After three years of piecing together hundreds of individual x-ray images, researchers were able to produce the first high-resolution picture of the five million atoms that make up a virus's protective shell. The yellow- and red-colored ribbons were highlighted to illustrate how four identical proteins join to form the building block of the blue-hued shell, or capsid, of the Ps V-F penicillin fungus-attacking virus.

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A, T, G, C and What?

New nucleotide discovered in mouse brain

Turns out life has more essential building blocks to play with than previously thought: researchers at Rockefeller University have discovered a new nucleotide in the mammalian DNA code. Remember good ol' adenine, thymine, guanine and cytosine? Well, the alphabet of our DNA sequence is about to receive a new letter. Meet 5-hydroxymethylcytosine; we aren't sure what it does or where it's located, but we know it's important -- really important.

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Stem Cells Easy on the Ears

According to a new study, the controversial, versatile cells could be used to reverse hearing loss

Thanks to a new technology that is still a little wet behind the ears, scientists now have reason to believe that stem cells have the potential to restore hearing loss. Although the cutting-edge science behind this project is still in the early research stage, scientist at the University of Sheffield have successfully induced fetal stem cells to behave like sensory hair cells and auditory neurons, two types of cells vital to a functioning auditory system.

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Cellular Lego Animations

Questions and answers with MIT's Lego educator

With her team, Kathy Vandiver, director of the Community Outreach and Education Program at MIT's Center for Environmental Health Sciences, creates eye-catching animations of cellular processes like meiosis, mitosis, and DNA translation and transcription, using Legos. These sophisticated simulations of what is going on in the cell are used as teaching aids for both school-aged and adult students, mainly to pique their interest in the subject matter at the beginning of a class.

Popular Science spoke to Dr. Vandiver about her Lego creations.

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December 2009: Best of What's New

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