Mice models can show the human response to vaccines for AIDS and other diseases
Testing AIDS vaccines can get ethically tricky in human volunteers. That's why MIT has engineered a more "humanized" mouse that has human immune cells, and could become the experimental model of choice involving vaccines for AIDS and other diseases.
The lab mice now display a wide array of human immune cells for the first time. Among the cells are Natural Killer (NK) cells that seek and destroy infected cells, as well as macrophages and dendritic cells that can swallow pathogens or recruit more immune cells to the fight.