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The Essential Guide to Stem Cells

Everything you need to know about the hottest topic in 
medicine, from big-league breakthroughs and new therapies to emerging health risks and the patients willing to take them

For more than a decade, researchers have touted stem cells as the most promising advance in medicine since antibiotics. And this winter, when President Obama lifted the Bush administration's ban on federal funding for embryonic-stem-cell research, talking heads buzzed that his decision could bring scientists that much closer to cures — not just treatments — for conditions like heart failure, spinal-cord injuries and Alzheimer's disease. Biologists around the world toasted their new prospects with champagne. "Lifting the ban will free us up to use additional cell lines," says Jack Kessler, director of the Feinberg Neuroscience Institute at Northwestern University. "It's very important for science."

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Why Your Flight Got Canceled

No, it’s not because the airline hates you

Last year, U.S. airlines canceled 21,000 flights. Or rather, a small cadre of guys canceled 21,000 flights. Every gate agent reports up the ladder at a given airline to a set of command-center managers. We spoke with a few of the people who make the big decisions to learn what factors influence whether they cancel a flight.

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Your quick and easy primer on just about everything

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The Latest Man-Made Organs

How science is rebuilding you, bit by bit

Almost 100,000 people languish on organ-transplant waiting lists. But new tissue-fabrication techniques should make swapping in a man-made liver as easy as snapping Lego bricks into place.

Blood vessels
Method: 3-D printer
When: 5 years
Gabor Forgacs, a tissue engineer at the University of Missouri, is making blood-vessel networks by culturing three types of vessel cells and loading them into a fridge-size bioprinter. This machine prints out the cells to build capillaries in preprogrammed patterns.

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The New Genetics

The latest science on how your cells make you who you are

Epigenetics is the idea that, contrary to decades of genetic theory, your genetic code isn’t the only thing that controls how your cells behave. Scientists now realize that chemicals and other environmental influences that can modify the physical structure of your DNA are at least as important as the actual genetic code. Even more surprising, these modifications are inheritable. It’s possible, for example, that your grandmother’s poor diet could affect your own health by making your DNA harder to read for the proteins that help maintain cellular functions.

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Learning From the Dead

Turns out that a body reveals more details about its death than once thought

Whether it’s the blue, ragged fingernails of a heroin-overdose victim or the scaly skin of someone poisoned by arsenic, a corpse bears signs that unveil the secrets behind its life and death. Right now, 40,000 John and Jane Does wait in morgues. Although accident and murder victims are 15 to 30 times as likely to be autopsied as those who die of natural causes, even run-of-the-mill autopsies can yield important information on how a person died. This data has important implications for public health and safety and the legislation that governs those areas of interest.

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Animal Myths Debunked

Scientific justice for maligned critters

Every animal has its rep. Rats are dirty; monkeys are cheeky; bats are blind. As anyone who's known an incurious cat can verify, though, these stereotypes are often false.

Here, modern scientific research takes a closer look at the truth about our animal friends.

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December 2009: Best of What's New

In our December issue, Popular Science names the 100 best innovations of the year: bombproof wallpaper, self-parking cars, the fastest helicopter, and 97 more. Plus inventor profiles and videos.

Check out the best of what's new here.

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